Oregon Grape Root

Berberis aquifolium

Goldenseal is one of the most heavily harvested wild flowers in the USA, as its reputation as an effective natural antibiotic has spread around the world. But its popularity has brought unacceptable pressure upon the plant and experts are now recommending alternatives. Oregon grape's historical and folk use is similar to that of goldenseal. In addition, Oregon grape has been used in the treatment of chronic skin conditions such as acne, psoriasis and eczema. As with goldenseal, the beneficial effects associated with Oregon grape are mainly due to the high levels of isoquinoline alkaloids present, particularly berberine.

ANTI-BIOTIC - Possibly the most important and celebrated property of berberine is its anti-biotic activity, being effective against a broad range of bacteria, protozoa and fungi. Berberine has shown efficacy against Chlamydia, E. coli, Salmonella typhi, Vibrio cholerae, Diplococcus pneumoniae, Shigella dysenteriae, and Candida Albicans and many more. Berberine's action against some of these pathogens is actually stronger than that of antibiotics commonly used for these foreign invaders. Berberine's action in inhibiting Candida, as well as pathogenic bacteria, prevents the spreading of a yeast that is a common side effect of antibiotic use.
ANTI-INFECTIVE - Berberine has demonstrated the ability to prevent bacterial adhesion to the host cells as well as its direct antibiotic effects. The berberine alkaloid of Oregon grape has been shown to inhibit the attachment of group -A streptococci to the lining of the throat. Berberine also offers benefits in cases of bladder infections, working best in an alkaline urine.
IMMUNO-STIMULATORY ACTION - Berberine has been shown to increase the blood supply to the spleen, promoting optimal activity in filtering the blood and releasing compounds that potentiate immune function. Berberine also activates macrophages the cells that engulf and destroy bacteria, viruses, tumour cells, and other undesirable matter. This effect on the blood supply classes berberine-containing plants as 'blood purifiers'.
FEVER-LOWERING ACTIVITY - Berberine containing plants are suitable in lowering fevers, as they appear to enhance the immune system's ability to handle fever-producing compounds produced by micro organisms.
ANTI-DIARRHEAL - A number of clinical studies have shown success in the treatment of acute diarrhoea. Berberine is effective in treating the majority of common intestinal infections, with results as good if not better than standard anti-biotic treatment. Along with the anti-microbial effects, berberine also blocks the action of toxins produced by certain bacteria, commonly experienced in diarrhoea caused by enterotoxins, cholera and traveller's diarrhoea.
LIVER SUPPORT - Berberine has been shown to stimulate the secretion of bile and bilirubin, and to correct metabolic abnormalities in patients with liver cirrhosis.

Dosage

250-500mg one to three times daily. Best taken away from food.

Potential applications

Diarrhoea, chronic candidiasis, conjunctivitis/blepharitis, gallstones, skin infections, parasites, poor digestion, psoriasis, urinary tract infections, cellular protection (anti-tumour), trachoma, chronic cholecystitis and liver disorders. Inflammatory states of the mucus membranes, peptic ulcers, colitis, anorexia and painful menstruation.

Known contraindications

Not recommended for use during pregnancy and lactation. Use should be restricted for two to three week periods.

Interactions

It is suggested that the efficacy of certain drugs i.e. Doxycycline and Tetracycline may be reduced when taken in conjunction with Oregon grape. High doses may interfere with B vitamin metabolism.

Use in conjunction with

Acidophillus, grapefruit seed extract, fibre complex, l-glutamine, digestive aid, green food blend, Echinacea, dandelion/burdock.

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